PDRN tau txais kev saib xyuas ntau ntxiv hauv kev saib xyuas tawv nqaij, tab sis lub npe INCI ib leeg tsis qhia tias cov khoom xyaw tau los ntawm qhov twg lossis tsim tawm li cas.
Hauv Uniproma cov khoom lag luam PDRN, ob qho tib si salmon-derived thiab recombinant PDRN raug txheeb xyuas tias yog Sodium DNA. Txawm hais tias sib koom tib lub npe INCI, ob txoj hauv kev sib txawv ntawm txoj kev tsim khoom, kev tswj xyuas zoo thiab kev nthuav dav ntawm kev muab khoom.
PDRN uas tau los ntawm ntses salmon muab qhov chaw pib tseem ceeb hauv kev tshawb fawb vim nws keeb kwm tau tsim los ntawm kev kho mob rov qab, kev siv tshuaj pleev ib ce thiab kev saib xyuas tawv nqaij. Los ntawm qhov kev siv no, Uniproma tau ua qhov kev txheeb xyuas thiab kev sib piv ntawm cov khoom lag luam PDRN thiab PN, xaiv 99 qhov zoo tshaj plaws gene fragments rau kev txhim kho recombinant ntxiv.
Tsis zoo li kev rho tawm ib txwm muaj los ntawm cov ntaub so ntswg biological, recombinant PDRN ua raws li txoj kev tsim khoom tswj hwm:
Kev xaiv cov kab ke ntawm lub hom phiaj → kev tsim cov plasmid → kev ua kom cov kab mob me me → kev ntes cov khoom lag luam → kev ntxuav cov dej ntws
Tom qab kev ua kom cov kua qaub (fermentation) tiav lawm, cov txheej txheem ntxuav kom huv si yog tsim los tshem tawm cov metabolites uas ua rau cov kua qaub (fermentation metabolites), cov protein ntawm cov hlwb ntawm tus tswv tsev (host-cell proteins) thiab cov DNA ntawm tus tswv tsev (host-cell DNA), nrog rau kev siv ion-exchange chromatography los ua ib kauj ruam ntxuav kom huv si ntxiv. Cov txheej txheem tswj hwm no txhawb nqa kev huv si, kev sib xws ntawm cov khoom sib xyaw thiab kev taug qab cov txheej txheem.
Kev tsim khoom raws li kev ua kom fermentation kuj txo qhov kev vam khom rau cov khoom siv biological raws caij nyoog thiab muab txoj hauv kev loj hlob los ntawm kev tsim khoom mus rau kev tsim khoom lag luam.
Kev ua haujlwm tau zoo kuj tau raug soj ntsuam hauv vivo. Tom qab 28 hnub ntawm kev siv ntawm 0.1%, recombinant PDRN tau qhia tias:
·TEWL txo 17.37%
· Kev txo qis ntawm erythema ntawm 12.40%
Kev txhim kho daim tawv nqaij elasticity ntawm 30.11%
· Kev txo cov kab mob wrinkle ntawm 46.67%
Cov kev tshawb pom no txhawb nqa nws lub peev xwm hauv kev kho qhov thaiv, ua kom so, ua kom ruaj khov thiab tiv thaiv kev laus.
Rau cov neeg tsim cov khoom thiab cov hom lag luam, kev ntsuam xyuas PDRN yog li ntawd txhais tau tias saib dhau lub npe INCI kom nkag siab txog lub kaw lus tsim khoom, kev tswj xyuas zoo thiab cov qauv muab khoom tom qab cov khoom xyaw.
Uniproma muab cov ntaub ntawv pov thawj, cov lus qhia txog kev tsim cov tshuaj, cov ntaub ntawv zoo thiab kev txhawb nqa kev lag luam rau kev tsim kho PDRN.
Lub sijhawm tshaj tawm: Lub Yim Hli-28-2026