| Lub npe lag luam | UniAPI-PBS |
| CAS | 1405-20-5 |
| Lub Npe Khoom | Polymyxin B sulfate |
| Qhov tsos | Dawb los yog yuav luag dawb hmoov |
| Kev yaj tau | Dej yaj tau |
| Daim Ntawv Thov | Tshuaj kho mob |
| Kev Ntsuas | Tus lej ntawm polymyxin B1, B2, B3 thiab B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
| Pob khoom | 1kg net rau ib lub thawv txhuas |
| Lub neej txee | 2 xyoos |
| Kev Khaws Cia | Khaws cia rau qhov chaw txias thiab qhuav, kom deb ntawm lub teeb. 2~8℃ rau kev khaws cia. |
| Cov Qauv Tshuaj |  |
Daim Ntawv Thov
Polyxin B sulfate yog ib qho tshuaj tua kab mob cationic surfactant, sib xyaw ntawm polyxin B1 thiab B2, uas tuaj yeem txhim kho qhov permeability ntawm cell membrane. Yuav luag tsis muaj ntxhiab. Rhiab rau lub teeb. Hygroscopic. Yaj hauv dej, me ntsis yaj hauv ethanol.
Cov nyhuv kho mob
Nws cov tshuaj tua kab mob thiab daim ntawv thov hauv kev kho mob zoo ib yam li polymyxin e. nws muaj cov teebmeem inhibitory lossis bactericidal rau cov kab mob Gram-negative, xws li Escherichia coli, Pseudomonas aeruginosa, paraescherichia coli, Klebsiella pneumoniae, acidophilus, pertussis thiab dysentery. Clinically, nws yog siv rau kev kis kab mob los ntawm cov kab mob rhiab heev, kev kis kab mob ntawm cov zis los ntawm Pseudomonas aeruginosa, qhov muag, trachea, meningitis, sepsis, hlawv kab mob, tawv nqaij thiab mucous membrane kab mob, thiab lwm yam.
kev ua haujlwm pharmacological
Nws muaj cov nyhuv tua kab mob rau Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus, enterobacter, Salmonella, Shigella, pertussis, pasteurella thiab Vibrio. Proteus, Neisseria, Serratia, pruvidens, Gram-positive bacteria thiab obligate anaerobes tsis muaj kev cuam tshuam rau cov tshuaj no. Muaj kev tiv thaiv hla ntawm cov tshuaj no thiab polymyxin E, tab sis tsis muaj kev tiv thaiv hla ntawm cov tshuaj no thiab lwm yam tshuaj tua kab mob.
Feem ntau nws yog siv rau qhov txhab, txoj hlab zis, qhov muag, pob ntseg, trachea kab mob los ntawm Pseudomonas aeruginosa thiab lwm yam Pseudomonas. Nws kuj tseem siv tau rau sepsis thiab peritonitis.
